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A big 'ol fat man ate everyone? A big bomb exploded? They starved to death? Murder? Genocide? A big 'ol lemon fell on them because deoxys got mad they give him money? :/
Gardenia poisoned the people who were ghosts because she wanted to be the gym leader. She was about to cure them with an antidote, but it was too late, which is why you can find an antidote in one of the trash cans...that is what happened.
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