Oh god. The world is FULL of awesome game quotes... XD Here's a few I scavenged from my archive...
"Did someone paint 'Taxi' on my 99?" Jaxon, Fire Fight, when asked to pick up ANOTHER informant.
"Do you think a minor thing like the end of the world could do me in?" Sabin, Final Fantasy VI
"By the way... I tried poisoning, strangulation, drowning... I even listened to improvised jazz music once, but that only made me WISH I was dead..." Windle Poons, in the end of Discworld II: Missing Presumed ?! (AKA Mortality Bytes!)
"LO! Behold the majesty of the tall stone pointy things! Who knows their mystic secrets? Who cares? Not me anyhow." Rincewind, commenting on the Pyramids, Discworld 2.
"Stop beating around the bush. Someone hiding information from me is the sixth most dangerous thing in this world!" Alys Brangwyn, Phantasy Star 4. Probably a mistranslation of something to the line of "When someone hides information from me, I'm the sixth most dangerous thing in the world."
"How strange! It's raining machines!" Raja, Phantasy Star 4, after the shuttle carrying the main group crashes on his temple-house.
"An droid, the droid, whatever." Raja, Phantasy Star 4, after Wren says he's not a mechanical doll but an Android.
"Am I a butterfly dreaming I'm a man... Or a bowling ball dreaming I'm a plate of sashimi? Never assume that what you see and feel is real!" Doreen, Chrono Trigger
"'The Mystery of Life' Vol. 841, Ch. 26. All life begins with Nu and ends with Nu... This is the truth! This is my belief! ...at least for now." Book by Belthasar, the Guru of Time, Chrono Trigger. (Because anything that involves Nus pwns.)
"Shields up, weapons online... Not equipped with shields? Well, then buckle up." Terran Battlecruiser Captain, Starcraft
"In case of a water landing, you may be used as a floation device." Terran Dropship Pilot, Starcraft
"If it weren't for these damned neural implants, you'd be a smoking crater by now." Terran Marine, Starcraft
"I'm about to drop the hammer and dispense some indiscriminate justice!" Terran Arclite Siege-Tank, Starcraft.
"What IS your major malfunction?!" Terran Arclite Siege-Tank, Starcraft.
"Who set all these lab monkeys free?" Terran Explorer-Class Science Vessel, Starcraft
"Do any of you fools know how to shut off this infernal contraption?" Terran Explorer-Class Science Vessel, Starcraft
"Checklist protocol... initiated. Running level 1 diagnostic. U.S.D.A. selected. F.D.I.C. approved. Checklist completed.. S.O.B." Terran Goliath, Starcraft
"This is very interesting... but stupid." The Valkyrie Pilot, StarCraft: Brood War